Assessment of ecological fidelity of human microbiome-associated mice in observational studies and an interventional trial
Matthew K. Wong, Eric Armstrong, Alya Heirali, Pierre H. H. Schneeberger, Helen Chen, Kyla Cochrane, Keith Sherriff, Emma Allen‐Vercoe, Lillian L. Siu, Anna Spreafico, Bryan A. Coburn
This study evaluates the ecological fidelity of HMA mice in replicating human microbiome responses to a microbial consortium, finding they are more similar to other mice than their human donors.
mBio · Sep 25, 2025Peer-reviewedMicrobiology