Author
Centre National de la Recherche ScientifiqueORCID 0000-0001-5263-1769Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Lia N’Guyen, Clara Tellez-Quijorna, Julien Vernerey…·Estelle Duprez
The paper characterizes NPM1-mutated AML subtypes using epigenomic and transcriptomic data, revealing distinct clinical and molecular features based on H3K27me3 levels at the HIST1 cluster.
Léonard Hérault, Mathilde Poplineau, Estelle Duprez, Élisabeth Rémy
The paper develops a Boolean network model of early hematopoiesis aging using scRNA-seq data and literature, identifying key regulatory changes in aged HSCs.
Léonard Hérault, Mathilde Poplineau, Adrien Mazuel…·Estelle Duprez
The paper analyzes single-cell RNA-seq data from young and aged mouse HSCs to show delayed differentiation and cell cycle imbalance in aged HSCs.
Mathilde Poplineau, Julien Vernerey, Nadine Platet…·Estelle Duprez
The paper identifies PLZF's role in limiting enhancer activity during hematopoietic progenitor aging by targeting H3K27ac.