GenomicsEpigenetics & ChromatinPeer-reviewed
H1.3 depletion in AML cells prompts H1.2 redistribution, chromatin remodeling and cell cycle defects
Clara Tellez-Quijorna, Lia N’Guyen, Núria Serna‐Pujol…·Estelle Duprez
Author
Estelle Duprez
Centre National de la Recherche ScientifiqueORCID 0000-0003-3810-5740Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 28 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- GenomicsbioRxivPreprint
Epigenenomic and transcriptomic characterization of NPM1-mutated CN-AML subtypes
Lia N’Guyen, Clara Tellez-Quijorna, Julien Vernerey…·Estelle Duprez
The paper characterizes NPM1-mutated AML subtypes using epigenomic and transcriptomic data, revealing distinct clinical and molecular features based on H3K27me3 levels at the HIST1 cluster.
1 citation - Systems BiologyBiosystemsPeer-reviewed
Logical modelling of myelofibrotic microenvironment predicts dysregulated progenitor stem cell crosstalk
Stephen P. Chapman, Estelle Duprez, Élisabeth Rémy
The paper constructs a logical model of the myelofibrotic microenvironment to predict how TPO and TLR signaling disrupt stem cell crosstalk and drive disease progression.
DOI 10.1016/j.biosystems.2023.104961 - Systems BiologyComputational and Structural Biotechnology JournalPeer-reviewed
A novel Boolean network inference strategy to model early hematopoiesis aging
Léonard Hérault, Mathilde Poplineau, Estelle Duprez, Élisabeth Rémy
The paper develops a Boolean network model of early hematopoiesis aging using scRNA-seq data and literature, identifying key regulatory changes in aged HSCs.
- GenomicsBMC BiologyPeer-reviewed
Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cell
Léonard Hérault, Mathilde Poplineau, Adrien Mazuel…·Estelle Duprez
The paper analyzes single-cell RNA-seq data from young and aged mouse HSCs to show delayed differentiation and cell cycle imbalance in aged HSCs.
- Molecular BiologyNucleic Acids ResearchPeer-reviewed
PLZF limits enhancer activity during hematopoietic progenitor aging
Mathilde Poplineau, Julien Vernerey, Nadine Platet…·Estelle Duprez
The paper identifies PLZF's role in limiting enhancer activity during hematopoietic progenitor aging by targeting H3K27ac.