Niamh Moriarty

This paper develops a hydrogel-based system to reprogram astrocytes into neurons by delivering reprogramming factors and valproic acid, enhancing neural repair.

The paper introduces NeuroGuard, a suicide gene system that selectively eliminates non-neuronal cells after transplantation, enhancing the safety and predictability of cell therapies.

This study identifies Netrin-1 as a DA-specific cue that enhances graft integration and functional recovery in Parkinsonian models without off-target effects.

This study shows that early viral delivery of GDNF improves survival and function of human stem cell grafts in Parkinson's disease models.