Author

Georg Werner

Ludwig-Maximilians-Universität MünchenORCID 0000-0001-5328-3049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Anja CapelliD· 2 shared Christian HaassiD· 2 shared Dieter EdbaueriD· 2 shared Dominik PaquetiD· 2 shared Gilbert Di PaoloiD· 2 shared Katrin Buschmann· 2 shared Marvin ReichiD· 2 shared Matthew J. SimoniD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Anja CapellORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 16, 2024

Enhanced legumain activity links progranulin deficiency to TDP-43 pathology in frontotemporal lobar degeneration

Sophie Robinson, Marvin Reich, Maria‐Teresa Mühlhofer…·Anja Capell

This study shows that reduced progranulin leads to increased legumain activity, which promotes TDP-43 pathology in FTLD, suggesting legumain as a therapeutic target.

5 citations

mousehuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 14, 2023

Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin

Marvin Reich, Matthew J. Simon, Beate Polke…·Christian Haass

Peripheral AAV-mediated delivery of brain-penetrant PGRN rescues TDP-43 pathology, neurodegeneration and motor phenotypes in FTLD-GRN models.

2 citations

mousehuman

𝕏 PostBluesky