Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer
Eun Jung Lee, Museong Kim, Sooyeon Park, Ji Hyeon Shim, Hyun‐Ju Cho, Jung-Ah Park, Kihyun Park, Dongeun Lee, Jeong‐Hwan Kim, Haeun Jeong, Fumio Matsuzaki, Seon‐Young Kim, Jaehoon Kim, Hanseul Yang, Jeong-Soo Lee, Jin Woo Kim
This study shows that disrupting Prox1 transfer to Müller glia in mice enables retinal regeneration and delays vision loss in a retinitis pigmentosa model.
Nature Communications · Mar 25, 2025Peer-reviewedDevelopmental Biology