Sandeep Singh

RTCpredictor identifies read-through chimeric RNAs from RNA sequencing data, outperforming existing tools in simulated and real datasets with faster execution and lower memory use.

The paper identifies 57 polymorphic chimeric RNAs, including SUZ12P1-CRLF3, and links one to Neurofibromatosis Type I through population-specific structural variants.

The paper identifies a female-specific chimeric RNA, UBA1-CDK16, and shows its role in myeloid differentiation and immune sexual dimorphism.

PEP2D predicts peptide secondary structure from PSSM evolutionary profiles, reaching Q3 83.5% on 3107 peptides against 76.9% for the protein-trained PSIPRED; a webserver is provided.

The paper evaluates seven docking methods on peptide-ligand complexes and finds AutoDock performs best with TOP poses, while performance differences are smaller with BEST poses.

The paper describes a method for predicting residue-residue contacts in CASP12 targets using predicted tertiary structures, achieving high precision in specific categories.