Yasushi Okamura

The paper uses a genetically engineered mouse to study Nav1.6 sodium channel turnover dynamics at the axon initial segment, revealing spatially asymmetric turnover and its role in AIS quality control.

This study reveals that PI(4,5)P2 binding to GABAARs at K311 is functionally significant, as shown through optogenetic manipulation and electrophysiology.

This study investigates how functionality and trafficking of KCNQ2/3 K+ channels are coupled, showing that low-activity mutations disrupt AIS targeting via ankyrin-G interaction.

This study shows that intracellular zinc dynamically regulates the Slo3 potassium channel in mouse spermatozoa during capacitation, inhibiting currents and mediating alkalinization-induced hyperpolarization.