Hein Putter

The paper introduces a penalized reduced rank regression model for multi-outcome survival data, finding a common metabolic risk score associated with age-related diseases using UK Biobank data.

The paper uses whole-slide ECM imaging to show dense fibrous matrix is linked to higher recurrence risk in Stage II colon cancer.

The paper introduces the AccelerAge framework, a statistical method for predicting biological age using time-to-event data, and evaluates it against existing predictors.

This paper examines the assumptions of cross-sectional biological age predictors and shows that a key assumption is untestable and can lead to unreliable results.