ImmunologyProceedings of the National Academy of SciencesPeer-reviewed
How persistent infection overcomes peripheral tolerance mechanisms to cause T cell-mediated autoimmune disease
Rose Yin, Samuel Melton, Eric S. Huseby…·Arup K. Chakraborty
The paper shows that persistent infections increase the likelihood of autoimmune T cell activation by exceeding a quorum threshold through molecular mimicry.
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