Gwennaele A. Fichant

rnaends is an R package for analyzing RNA-end sequencing data to study RNA metabolism, providing tools for preprocessing, mapping, quantification, and downstream analysis of RNA ends.

The paper identifies aRNase J, a 5’-3’ exoribonuclease in Archaea, as part of a complex with ASH-Ski2 helicase and the RNA exosome, suggesting its role in RNA surveillance and translation.

The paper develops a dynamic model of competence in Streptococcus pneumoniae, revealing regulatory mechanisms and experimentally confirming predictions about gene products and protein interactions.

The paper characterizes the diversity of TnpAY1 proteins, identifies their classification into subclasses, and explores their potential roles in ssDNA processing and horizontal gene transfer.