Tomas Caetano

The paper shows oxidative DNA damage directly affects gene transcription through repair-dependent mechanisms using RNA-Seq, ChIP-seq, and chemogenetic approaches.

The paper identifies a new class of short box C/D-like RNAs in mice, expanding the known repertoire of SNORDs and raising questions about their function and evolution.

rnaends is an R package for analyzing RNA-end sequencing data to study RNA metabolism, providing tools for preprocessing, mapping, quantification, and downstream analysis of RNA ends.

The paper identifies Sni445 as a novel factor that recruits snR4 and snR45 snoRNPs to 90S pre-ribosomes, enabling Kre33-mediated acetylation of 18S rRNA.