Deqiang Zhang

PISCO improves codon optimization by integrating protein structure and host-specific codon usage, enhancing solubility and expression.

This study uses a deep learning-based MLFF to simulate the PETase-catalyzed reaction with DFT-level accuracy, capturing key events and free energy barriers consistent with experiments and previous QM/MM studies.

QuantaMind MD provides quantum-accurate molecular dynamics simulations for proteins, enabling accurate structure optimization and ligand interaction modeling.