Author

Won Hee Ryu

Oregon Health & Science UniversityORCID 0000-0001-5484-9905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

Adam J. BroermaniD· 1 shared Alex KangiD· 1 shared Asim K. BeraiD· 1 shared Aza AlleniD· 1 shared Banumathi SankaraniD· 1 shared Christoph PollmanniD· 1 shared D.M. Nirosh UdayangaiD· 1 shared Daniel M. ZuckermaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Adam J. BroermanORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintDec 30, 2025

Design, synthesis and profiling of highly potent antivirals targeting emerging drug-resistant HIV-1 variants

Nicolas Jamey, D.M. Nirosh Udayanga, Huanchun Zhang…·Zhengqiang Wang

This paper designs and synthesizes LEN analogs with improved potency against HIV-1 and resistant variants like M66I, showing significant enhancement in antiviral activity.

1 citation

virusexperimental assay

𝕏 PostBluesky

BiochemistryNaturePeer-reviewedSep 24, 2025

Design of facilitated dissociation enables control over cytokine signaling duration

Adam J. Broerman, Christoph Pollmann, Yang Zhao…·David A. Baker

The paper designs proteins with controlled dissociation rates by introducing strained excited states, enabling rapid cytokine receptor dissociation.

29 citationstop 1%

experimental assayprotein folding & dynamics

𝕏 PostBluesky