Author

Holly K. Harris

Baylor College of MedicineORCID 0000-0001-5512-755XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Boxun ZhaoiD· 2 shared Jenny F. LaiiD· 2 shared Timothy W. YuiD· 2 shared Tojo NakayamaiD· 2 shared Ada HamoshiD· 1 shared Aikaterini ChatzipliiD· 1 shared Alan H. BeggsiD· 1 shared Alice PoissoniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Boxun ZhaoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 27, 2025

Multi-omic analysis of the ciliogenic transcription factor RFX3 reveals a role in promoting activity-dependent responses via enhancing CREB binding in human neurons

Jenny F. Lai, Didem Demirbas, Kaitlyn Phillips…·Timothy W. Yu

This study investigates RFX3's role in human neurons, showing that monoallelic loss disrupts synaptic gene expression and activity-dependent responses by impairing CREB binding.

6 citations

humanbulk RNA-seq

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Genetic & Genomic MedicineJournal of Autism and Developmental DisordersPeer-reviewedNov 28, 2022

Latent class analysis identifies distinctive behavioral subtypes in children with fragile X syndrome

Walter E. Kaufmann, Melissa Raspa, Carla Bann…·Stephanie M. Morris

The paper uses latent class analysis to identify distinct behavioral subtypes in children with fragile X syndrome, revealing clinically meaningful groups with unique cognitive and behavioral profiles.

14 citations

humanstatistical model

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Genetic & Genomic MedicineGenetics in MedicinePeer-reviewedMar 3, 2021

Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior

Holly K. Harris, Tojo Nakayama, Jenny F. Lai…·Timothy W. Yu

The paper identifies RFX3, RFX4, and RFX7 mutations as causes of neurodevelopmental disorders including autism, ADHD, and intellectual disability, and links these genes to ASD risk genes through bioinformatic analysis.

84 citationstop 3%

humanbulk RNA-seq

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