Aikaterini Chatzipli

Hybrid transcriptome assembly and annotation of Japanese macaque prefrontal cortex

The paper presents a hybrid transcriptome assembly and annotation of Japanese macaque prefrontal cortex using short- and long-read RNA sequencing data.

Multi-omic analysis of the ciliogenic transcription factor RFX3 reveals a role in promoting activity-dependent responses via enhancing CREB binding in human neurons

This study investigates RFX3's role in human neurons, showing that monoallelic loss disrupts synaptic gene expression and activity-dependent responses by impairing CREB binding.

Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer PDXs

The paper trains an ensemble classifier to predict cetuximab sensitivity in colorectal cancer PDXs using multi-omic data, achieving high accuracy and demonstrating its utility for therapeutic biomarker development.

APOBEC3B-dependent kataegis and TREX1-driven chromothripsis in telomere crisis

This study identifies TREX1 and APOBEC3B as key drivers of chromothripsis and kataegis during telomere crisis in cancer.