Kevin Yuk-Lap Yip

This paper develops a cross-organism framework for enhancer prediction using Drosophila STARR-seq data and supervised machine learning, validated in mouse and human with 153 enhancers.

CQF-deNoise reduces memory usage for k-mer counting in single-cell RNA-seq, enabling faster clustering with accuracy comparable to CellRanger.

This study evaluates the impact of 5-hydroxymethylcytosine (5hmC) and PDR on gene expression inference using WGBS and oxWGBS data from normal and tumor tissues.

OMSV identifies large structural variations from optical maps with high accuracy, outperforming existing methods and detecting many missed by sequencing.