GeneticsbioRxivPreprint
Genetic Fine-mapping with Dense Linkage Disequilibrium Blocks: genetics of nicotine dependence
Chen Mo, Zhenyao Ye, Kathryn S. Hatch…·Shuo Chen
This paper introduces a novel ℓ0 graph norm shrinkage algorithm for genetic fine-mapping, demonstrating improved sensitivity and reduced false positives in identifying causal variants for nicotine dependence.
DOI 10.1101/2020.12.10.420216