Author
Broad InstituteORCID 0000-0001-5542-0254Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
C. Guo, Uma P. Arora, Xiaoheng Cheng…·Vijay G. Sankaran
This study identifies a BACH2-NRF2 axis regulating fetal hemoglobin activation through genetic and functional analyses in a large multi-ancestry cohort.
Zain Ali, Aitzkoa Lopez de Lapuente Portilla, Guðmar Þorleifsson…·Björn Nilsson
The paper uses population-scale Ig genetics to identify genetic associations and map their effects on the human B-cell system, revealing new genes and regulatory mechanisms in humoral immunity.
Aitzkoa Lopez de Lapuente Portilla, Ludvig Ekdahl, Guðmar Þorleifsson…·Björn Nilsson
BloodVariome identifies 259 genetic associations across 127 immune cell populations in 11,983 individuals, revealing fine-grained genetic compartmentalization of the immune system.
Aitzkoa Lopez de Lapuente Portilla, Ludvig Ekdahl, Caterina Cafaro…·Björn Nilsson
A genome-wide association study identifies DNA variants influencing HSPC levels in human blood, with PPM1H as a novel regulator affecting stem cell subpopulations.
Erik L. Bao, Satish Kumar Nandakumar, Xiaotian Liao…·Vijay G. Sankaran
This study identifies 14 genome-wide significant loci and a polygenic signature for myeloproliferative neoplasms, implicating hematopoietic stem cell function and self-renewal in disease risk.
Linnea Järvstråt, Ram Ajore, Anna‐Karin Wihlborg…·Björn Nilsson
This paper develops a computational method to deconvolve gene expression in leukemic cell hierarchies and identifies markers for AML-LSC.