Molecular BiologybioRxivPreprint
Anti-inflammatory effects of WFS1 in pancreatic beta-cells
Shuntaro Morikawa, Lindsey Blacher, Chinyere Onwumere, Fumihiko Urano
This study shows that WFS1 deficiency in pancreatic beta-cells increases inflammation, leading to ER stress and cell death, and identifies potential therapeutic targets for Wolfram syndrome.
DOI 10.1101/2022.02.09.479773