Jack da Silva

This paper reanalyzes dog cancer mortality data to suggest that single driver mutations may initiate cancer, with somatic mutation rates increasing with body weight and 56% of cancers linked to somatic cell divisions.

The paper tests hypotheses about adaptive cancer suppression by analyzing how stem cell mutation rates and driver mutations relate to tissue-specific cancer risks.

This study tests an analytical life history model of optimal size using mammal life history and phylogeny data, showing it explains macroevolutionary patterns of body size evolution.