Author

Stefano Testa

Beth Israel Deaconess Medical CenterORCID 0000-0001-5632-5021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aastha PaliD· 2 shared Anusha K. KalbasiiD· 2 shared Everett James ModingiD· 2 shared Ada WongiD· 1 shared Ajay SubramanianiD· 1 shared Christopher S. SeetiD· 1 shared Danielle Graham· 1 shared Deepa Waghray· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Aastha PalORCID

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2 papers

Recent·Most cited

ImmunologyImmunityPeer-reviewedNov 21, 2025

IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy

Hua Jiang, Sam P. Limsuwannarot, Kayla R. Kulhanek…·Anusha K. Kalbasi

The paper shows that T cells engineered with IL-9R have better tissue infiltration, stemness, and anti-tumor activity compared to those with an orthogonal IL-9 receptor, due to stronger and more specific JAK/STAT signaling.

17 citationstop 2%

mouseexperimental assay

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Cancer BiologyGenome MedicinePeer-reviewedAug 14, 2025

SCAN-ACT: Adoptive T Cell Therapy Target Discovery Through Single-Cell Transcriptomics

Stefano Testa, Aastha Pal, Ajay Subramanian…·Everett James Moding

SCAN-ACT identifies and prioritizes T cell therapy targets for solid tumors using single-cell transcriptomics and multi-omics data, validating targets through experimental methods.

6 citations

humanscRNA-seq

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