NeurosciencebioRxivPreprint
Mitochondrial OPA1 deficiency causes reversible defects in adult neurogenesis-associated spatial memory in mice
Trinovita Andraini, Lionel Moulédous, Petnoï Petsophonsakul…·Marie‐Christine Miquel
This study shows that mitochondrial OPA1 deficiency in mice causes early spatial memory impairments linked to adult neurogenesis defects, which can be reversed by exercise or pharmacological treatment.
DOI 10.1101/2021.11.16.468792