Author

Sam Samuel Franciscus Allegonda van Knippenberg

KU LeuvenORCID 0000-0001-5656-3046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mairim Alexandra SolísiD· 2 shared Sherif KhodeeriD· 2 shared Vincent PasqueiD· 2 shared Andrea Drusin· 1 shared Anna OsnatoiD· 1 shared Anne WenzeliD· 1 shared Antonina MikorskaiD· 1 shared Chiara ColantuonoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersDevelopmental Biology

Mairim Alexandra SolísORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 25, 2026

SWI/SNF-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids

Sam Samuel Franciscus Allegonda van Knippenberg, Maria Tryfonos, Joke De Busscher…·Vincent Pasque

This study shows that SWI/SNF chromatin remodellers are critical for lineage specification in human embryos and blastoids by regulating enhancer accessibility and transcription factor binding.

DOI 10.64898/2025.12.01.691499

humanChIP-seq

Cell BiologybioRxivPreprintJan 17, 2025

Feeder-free culture of naive human pluripotent stem cells retaining embryonic, extraembryonic and blastoid generation potential

Giada Rossignoli, Michael Oberhuemer, Ida Sophie Brun…·Graziano Martello

This study develops a feeder-free serum-coated system for culturing naive human pluripotent stem cells, maintaining their developmental potential and reducing contamination and mutations.

2 citations

humanbulk RNA-seq