Author

Alexander Tielemans

Icahn School of Medicine at Mount SinaiORCID 0000-0001-5671-2144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Deanna L. BensoniD· 2 shared George W. HuntleyiD· 2 shared Ayan HusseiniD· 1 shared Christopher A. GuevaraiD· 1 shared Mark G. BaxteriD· 1 shared Swati GuptaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Deanna L. BensonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJul 5, 2024

Parkinson's-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity

Swati Gupta, Alexander Tielemans, Christopher A. Guevara…·Deanna L. Benson

This study shows that the LRRK2-G2019S mutation alters AMPAR trafficking and composition in striatal projection neurons, specifically affecting GluA1 subunits and impairing synaptic plasticity.

10 citations

mouseproteomics

𝕏 PostBluesky

NeuroscienceExperimental NeurologyPeer-reviewedSep 1, 2022

Cognitive Deficits and Altered Cholinergic Innervation in Young Adult Mice Carrying a Parkinson's Disease LRRK2-G2019S Knockin Mutation

Ayan Hussein, Alexander Tielemans, Mark G. Baxter…·George W. Huntley

This study shows that LRRK2-G2019S mutation in mice causes cognitive deficits and reduced cholinergic innervation in brain regions linked to executive function.

19 citations

mousestatistical model

𝕏 PostBluesky