Thiago B Bruder-Nascimento

This study shows that activating Beclin1 prevents aldosterone-induced cardiovascular damage by restoring autophagy, protecting vascular and cardiac function.

This study shows that Ang II enhances CCL5/CCR5 signaling, leading to mitochondrial dysfunction and oxidative stress in vascular smooth muscle cells, contributing to vascular injury in hypertension.

This study identifies CASC15 as a regulator of vascular smooth muscle cell growth fate and vascular remodeling, showing it controls proliferation versus hypertrophy through mitotic fidelity.

This study shows that progranulin deficiency worsens age-related vascular damage in mice, affecting endothelial function and vascular remodeling.