Author

Gustavo Félix Pimenta

Universidade de São PauloORCID 0000-0001-6390-3803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ariane Bruder‐NascimentoiD· 2 shared Thiago B Bruder-NascimentoiD· 2 shared Adeyeye I. HaastrupiD· 1 shared André Ferreira do NascimentoiD· 1 shared Angela Russ· 1 shared Carlos Renato TirapelliiD· 1 shared Cynthia St. HilaireiD· 1 shared Juliano V Alves· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

Ariane Bruder‐NascimentoORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintJul 22, 2026

CCR5/CCL5 Links Mitochondrial Dysfunction to Angiotensin II Vascular Injury

Gustavo Félix Pimenta, Ariane Bruder‐Nascimento, Tyler Beling…·Thiago B Bruder-Nascimento

This study shows that Ang II enhances CCL5/CCR5 signaling, leading to mitochondrial dysfunction and oxidative stress in vascular smooth muscle cells, contributing to vascular injury in hypertension.

DOI 10.64898/2026.03.10.710946

mouseexperimental assay

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Cell BiologybioRxivPreprintNov 25, 2025

Progranulin deficiency aggravates aging-induced vascular injury

Renata de Azevedo Melo Luvizotto, André Ferreira do Nascimento, Gustavo Félix Pimenta…·Thiago B Bruder-Nascimento

This study shows that progranulin deficiency worsens age-related vascular damage in mice, affecting endothelial function and vascular remodeling.

DOI 10.1101/2025.11.25.690611

mousebulk RNA-seq

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