Author

Elena Gallo MacFarlane

Johns Hopkins UniversityORCID 0000-0001-5677-6842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Harry C. DietziD· 2 shared Benjamin E. KangiD· 1 shared Caitlin J. BoweniD· 1 shared Djahida BedjaiD· 1 shared Elaine C. Davis· 1 shared Graham RykieliD· 1 shared Jefferson James DoyleiD· 1 shared Juan F. CalderóniD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Harry C. DietzORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintFeb 12, 2021

Epigenetic modulation in the pathogenesis and treatment of inherited aortic aneurysm conditions

Benjamin E. Kang, Rustam Bagirzadeh, Djahida Bedja…·Harry C. Dietz

This study shows that epigenetic modulation, specifically targeting H3K27 acetylation, can reduce aortic root aneurysm in SGS and MFS mouse models by inhibiting TGFβ target gene expression.

1 citation

mouseexperimental assay

𝕏 PostBluesky

GeneticsJournal of Clinical InvestigationPeer-reviewedOct 22, 2019

Targetable cellular signaling events drive arterial rupture in knock-in mouse models of vascular Ehlers-Danlos Syndrome

Caitlin J. Bowen, Juan F. Calderón, Zachary Burger…·Harry C. Dietz

The paper identifies signaling pathway abnormalities in vEDS mouse models that contribute to arterial rupture.

82 citationstop 4%

mouseexperimental assay

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