Elaine C. Davis

Arterial Elastin Abundance, Rather Than Orthologue Origin, Modulates Medial Arterial Calcification in Matrix Gla Protein-Deficient Mice

The paper shows that arterial elastin abundance, not its origin, affects medial calcification in MGP-deficient mice, with reduced elastin delaying calcification and human elastin restoring it.

Targetable cellular signaling events drive arterial rupture in knock-in mouse models of vascular Ehlers-Danlos Syndrome

The paper identifies signaling pathway abnormalities in vEDS mouse models that contribute to arterial rupture.