GeneticsbioRxivPreprint
Epigenetic modulation in the pathogenesis and treatment of inherited aortic aneurysm conditions
Benjamin E. Kang, Rustam Bagirzadeh, Djahida Bedja…·Harry C. Dietz
This study shows that epigenetic modulation, specifically targeting H3K27 acetylation, can reduce aortic root aneurysm in SGS and MFS mouse models by inhibiting TGFβ target gene expression.
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