Cancer BiologyCellular SignallingPeer-reviewed
Phosphoglycerate mutase 5 regulates lipid metabolism and mitochondrial homeostasis in hepatocellular cancer cells
Praveen Kumar Guttula, Ganesan Muthusamy, Chin‐Chi Liu…·Andrea N. Johnston
This study shows that PGAM5 loss in hepatocellular cancer cells disrupts lipid metabolism and mitochondrial homeostasis by altering bioenergetics and phospholipid pathways.
DOI 10.1016/j.cellsig.2026.112833