Cancer BiologybioRxivPreprint
YAP1 Depletion Enhances TAZ and its Complexation with TEAD4 and AP-1 Heterodimer C-JUN/FOSB to Promote Gastric Cancer Progression and Metastases
Jingjing Wu, Dipti Athavale, Curt Balch…·Shumei Song
This study shows that inhibiting both YAP1 and TAZ in gastric cancer peritoneal metastases reduces tumor growth and progression by blocking their interactions with TEAD4 and AP-1 complexes.
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