Gengyi Zou

This study shows that ARID1A deficiency increases centromeric RNA transcription, causing chromosomal instability and enhancing the effectiveness of PKMYT1 inhibitors through RNA sensing.

This study shows that inhibiting both YAP1 and TAZ in gastric cancer peritoneal metastases reduces tumor growth and progression by blocking their interactions with TEAD4 and AP-1 complexes.

This study shows that CRACD inactivation in gastric cancer leads to immune evasion via oxidative stress-activated PD-L1, suggesting HIF1 and PD-L1 as therapeutic targets.