Author

Mehran Dastmalchi

McGill UniversityORCID 0000-0001-5693-6324Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Plant Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Lee Marie RaytekiD· 2 shared Meha SharmaiD· 2 shared Brandon Corey Saltzman· 1 shared Christopher J. ThibodeauxiD· 1 shared Lan LiuiD· 1 shared Sibei QiniD· 1 shared Soon Goo LeeiD· 1 shared Stéphane BayeniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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2 shared papersPlant Biology

Lee Marie RaytekORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 27, 2026

Dynamic structural changes and inhibition of insect delta and epsilon glutathione S-transferases by ethacrynic acid and permethrin

Meha Sharma, Sibei Qin, Christopher J. Thibodeaux, Mehran Dastmalchi

This study analyzes insect GSTs to identify structural and functional differences that could inform the development of selective insecticides.

DOI 10.64898/2026.07.24.740637

protein structurestatistical model

𝕏 PostBluesky

Plant BiologybioRxivPreprintNov 18, 2025

Discovery of pseudobaptigenin synthase, completing the (-)-maackiain biosynthetic pathway

Lee Marie Raytek, Lan Liu, Stéphane Bayen, Mehran Dastmalchi

The paper identifies TpPbS/CYP76F319, a cytochrome P450 enzyme that catalyzes methylenedioxy bridge formation in the biosynthesis of (-)-maackiain in red clover.

DOI 10.1101/2025.11.18.689130

plant (other)metabolomics

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Synthetic BiologyBiochemical Engineering JournalPeer-reviewedJul 3, 2025

Chalcone isomerase-like impedes the lactone shunt and enhances flux partitioning in a bifurcated pathway towards isoflavonoid biosynthesis

Lee Marie Raytek, Brandon Corey Saltzman, Meha Sharma…·Mehran Dastmalchi

This study shows that Chalcone isomerase-like proteins reduce lactone by-product formation and increase target compound titers in engineered yeast for isoflavonoid biosynthesis.

5 citations

plant (other)experimental assay

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