High-throughput Kinetics using Capillary Electrophoresis and Robotics (HiKER) platform used to Study T7, T3, and Sp6 RNA Polymerase Misincorporation
Zachariah I. Carter, William B. O’Brien, Sean R. Lund, Andrew F. Gardner
The paper introduces HiKER, a high-throughput platform for measuring RNA polymerase kinetics, showing differences in misincorporation rates among T7, T3, and Sp6 RNAPs.
PLoS ONE · Dec 2, 2024Peer-reviewedBiochemistry