Author

William B. O’Brien

Carnegie Mellon UniversityORCID 0009-0004-9484-0437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam W. FeinbergiD· 1 shared Andrew F. GardneriD· 1 shared Caner DikyoliD· 1 shared Durva A. NaikiD· 1 shared Jacqueline M. BlileyiD· 1 shared Maria A. StangiD· 1 shared Sean R. LundiD· 1 shared Syed Faaz AshrafiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

Adam W. FeinbergORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 20, 2026

Multi-Modal photoFRESH: Light-Pipe Embedded Printing of Heterogeneous Hydrogel and Tissue Architectures

Caner Dikyol, William B. O’Brien, Maria A. Stang…·Adam W. Feinberg

The paper introduces multi-modal photoFRESH, a 3D bioprinting technique that enables precise control of crosslinking, stiffness, and biomolecular tethering through localized photochemistry, resulting in structurally complex and heterogeneous tissue constructs.

DOI 10.64898/2026.07.19.738036

experimental assay

𝕏 PostBluesky

BiochemistryPLoS ONEPeer-reviewedDec 2, 2024

High-throughput Kinetics using Capillary Electrophoresis and Robotics (HiKER) platform used to Study T7, T3, and Sp6 RNA Polymerase Misincorporation

Zachariah I. Carter, William B. O’Brien, Sean R. Lund, Andrew F. Gardner

The paper introduces HiKER, a high-throughput platform for measuring RNA polymerase kinetics, showing differences in misincorporation rates among T7, T3, and Sp6 RNAPs.

4 citations

proteomicsexperimental assay

𝕏 PostBluesky