Lysine Decarboxylation aids in UPEC intracellular survival in the early stages of urinary tract infection
Michelle Wiebe, Seth A. Reasoner, Tomas A. Bermudez, John R. Brannon, Grace H Morales, Faith Guice, Erin Q. Jennings, Jeffrey C. Rathmell, Maria Hadjifrangiskou
This study identifies AR4 (cadA) as critical for UPEC survival during early intracellular infection by showing its induction and role in lysosome resistance.
bioRxiv · Apr 25, 2025 · PreprintMicrobiology