Author

Cheng Wu

First Affiliated Hospital of Guangzhou Medical UniversityORCID 0000-0001-5733-793XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Cheng Wu1 paper · Sir Run Run Shaw Hospital

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

D. Z. Li· 1 shared Fengyin LiangiD· 1 shared Guang-qing Xu· 1 shared Haipeng ZhuiD· 1 shared Ke SiiD· 1 shared Ningning Sun· 1 shared Qun ZhangiD· 1 shared Shuai MaoiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

D. Z. Li

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 19, 2026

Divergent malignant evolution converges on shared immunosuppressive ecosystems through tumor-intrinsic TMED2-ADAR1-dependent complement signalling in multifocal hepatocellular carcinoma

Cheng Wu, Ke Si, Shuai Mao…·Wenliang Zhang

This study identifies shared immunosuppressive mechanisms in multifocal hepatocellular carcinoma despite divergent tumor evolution, highlighting a TMED2-ADAR1-C3/C5 complement axis as a potential therapeutic target.

DOI 10.64898/2026.04.21.719788

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NeurosciencebioRxivPreprintJan 31, 2020

Glutamate and γ-aminobutyric acid differentially modulate glymphatic clearance of amyloid β through pulsation- and aquaporin-4 dependent mechanisms

Cheng Wu, Yiwei Feng, Qun Zhang…·Guang-qing Xu

This study shows that glutamate and GABA modulate glymphatic clearance of amyloid β through distinct mechanisms involving pulsation and AQP4, with potential therapeutic implications for Alzheimer's disease.

4 citations

mouseexperimental assay

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