Systems BiologyCell ReportsPeer-reviewed
Molecular Noise-Filtering in the β-adrenergic Signaling Network by Phospholamban Pentamers
Daniel Koch, Alexander Alexandrovich, Florian Funk…·Mathias Gautel
The paper shows that PLN pentamers act as noise-filters in β-adrenergic signaling by regulating monomer phosphorylation and stabilizing SERCA activity despite PKA activity fluctuations.
10 citations