Author

Yael Nechemia‐Arbely

University of PittsburghORCID 0000-0001-5753-5485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Lior Lumerman· 2 shared Megan A. Mahlke· 2 shared Angela EnriqueziD· 1 shared Cy ChittendeniD· 1 shared Jonas KoeppeliD· 1 shared Karen H. MigaiD· 1 shared Kylie Zaffina· 1 shared Nicolas AltemoseiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Lior Lumerman

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2 papers

Recent·Most cited

Cell BiologyCell ReportsPeer-reviewedAug 1, 2026

Evolution and instability of human centromeres are accelerated by heterochromatin boundary loss and CENP-A overexpression

Megan A. Mahlke, Angela Enriquez, Lior Lumerman…·Yael Nechemia‐Arbely

The paper shows that human centromeres and neocentromeres evolve epigenetically, with instability linked to loss of heterochromatin boundaries and CENP-A overexpression.

1 citation

humanDNA methylation

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Molecular BiologyLife Science AlliancePeer-reviewedJan 3, 2023

Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells

Megan A. Mahlke, Lior Lumerman, Peter Ly, Yael Nechemia‐Arbely

The paper shows that CENP-A is precisely maintained at the same genomic positions through DNA replication in human cells, but its location varies between cell lines.

11 citations

humanDNA methylation

𝕏 PostBluesky