Author

Ryan Michael Carr

Mayo ClinicORCID 0000-0001-5762-367XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carlo C. MaleyiD· 2 shared Luis Humberto CisnerosiD· 2 shared Martín E. Fernández-ZapicoiD· 2 shared Merih Deniz ToruneriD· 2 shared Alex Xiao· 1 shared Andrea V. Maraone GarzaroiD· 1 shared Ben GeorgeiD· 1 shared Christopher HartleyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Carlo C. MaleyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 3, 2025

Spatial Conformation of Pancreatic Cancer Is Associated with Disease Recurrence after Curative-Intent Total Neoadjuvant Therapy

Luis Humberto Cisneros, Merih Deniz Toruner, Zafar Siddiqui…·Ryan Michael Carr

This paper quantifies spatial cancer-stroma topology in post-TNT PDAC and shows it independently predicts disease-free survival better than traditional response assessments.

DOI 10.1101/2025.11.03.686383

humanimaging

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 22, 2025

Tumor Landscape Analysis: An Ecologically Informed Framework to Understand Tumor Microenvironments

Luis Humberto Cisneros, Merih Deniz Toruner, Martín E. Fernández-Zapico…·Ryan Michael Carr

The paper introduces TLA, a computational framework using ecological principles to analyze tumor spatial heterogeneity and link it to clinical outcomes.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky