siRNAs targeting a chromatin-associated RNA induce its transcriptional silencing in human cells
Julien Ouvrard, Lisa Muniz, Estelle Nicolas, Didier Trouche
This study shows that siRNAs targeting a chromatin-associated RNA can induce its transcriptional silencing in human cells through cis-specific base pairing.
bioRxiv · May 11, 2022 · PreprintMolecular Biology