Marion Aguirrebengoa

The paper shows oxidative DNA damage directly affects gene transcription through repair-dependent mechanisms using RNA-Seq, ChIP-seq, and chemogenetic approaches.

The paper shows that premature termination of transcription by RNA polymerase I limits rRNA production and that a mutant polymerase, SuperPol, reduces this termination, increasing rRNA output.

The paper identifies Sni445 as a novel factor that recruits snR4 and snR45 snoRNPs to 90S pre-ribosomes, enabling Kre33-mediated acetylation of 18S rRNA.

The paper identifies PERIOD proteins as regulators of TC-DSB repair by anchoring DSBs to the nuclear envelope, linking circadian rhythms to DNA repair mechanisms.

The paper identifies a unique molecular signature of Olig2-expressing astrocytes through transcriptome profiling and differential gene expression analysis.

The paper shows Neurog1 controls olfactory organ morphogenesis through cxcr4b in zebrafish.

The paper shows that circular ANRIL isoforms switch from repressing to activating p15/CDKN2B expression during RAF1-induced senescence by altering Polycomb protein interactions.

This study shows BLM promotes Homologous Recombination at DSBs in active chromatin but switches to Break-Induced Replication when R-loop dissolution is impaired, reducing cell viability.