BiomarkerKB integrates and standardizes biomarker data from multiple sources to enable structured exploration and discovery of biomarker-disease relationships.

Patterns · Aug 1, 2026Peer-reviewedBioinformatics

OBO Foundry in 2021: Operationalizing Open Data Principles to Evaluate Ontologies

Rebecca Jackson, Nicolas Matentzoglu, James A. Overton, Randi Vita, James P. Balhoff, Pier Luigi Buttigieg, Seth Carbon, Mélanie Courtot, Alexander D. Diehl, Damion Dooley, William D. Duncan, Nomi L. Harris, Melissa Anne Haendel, Suzanna Lewis, Darren A. Natale, , Bjoern Peters

The paper describes how the OBO Foundry formalized its principles into operational rules and implemented automated checks to evaluate ontology compliance, improving interoperability and quality.

Database · Oct 1, 2021Peer-reviewedBioinformatics

COVID-19 Biomarkers in research: Extension of the OncoMX cancer biomarker data model to capture biomarker data from other diseases.

Nikhita Gogate, Daniel Lyman, Amanda L. Bell, Edmund S. Cauley, Keith A. Crandall, Ashia Joseph, Robel Kahsay, Darren A. Natale, Lynn M. Schriml, Sabyasach Sen, Raja Mazumder

The paper extends a cancer biomarker data model to create a COVID-19 biomarker knowledgebase, integrating 138 biomarkers and 265 type combinations with ontological annotations.

Briefings in Bioinformatics · Apr 27, 2021Peer-reviewedBioinformatics