Edmund S. Cauley

This study establishes patient-derived KS xenografts that maintain KSHV infection and recapitulate KS tumor gene signatures, enabling analysis of tumor microenvironment cell communications.

The paper shows that zebrafish inpp5ka and inpp5kb, duplicated from whole genome duplication, have diverged in expression and function, with inpp5ka more closely related to human INPP5K and inpp5kb losing catalytic activity.

This study identifies differentially expressed glycosyltransferases across 16 cancers using a multifaceted genomics approach and integrates findings with experimental evidence.

The paper extends a cancer biomarker data model to create a COVID-19 biomarker knowledgebase, integrating 138 biomarkers and 265 type combinations with ontological annotations.