Jérôme Bourien

This study investigates the developmental plasticity of cochlear inner hair cell ribbon synapses using live-cell imaging, revealing activity-dependent mechanisms in their structural maturation.

The paper shows that auditory feature representations develop gradually through stages of the auditory pathway, with specific improvements at certain stages.

The paper shows that spatial representations, not temporal patterns, are necessary for sensory learning in mice using optogenetic stimulation and neural recordings.

The paper uses PSTR to predict adaptation and spontaneous firing rates in human auditory nerve fibers, showing agreement with single-unit recordings in animals.

The paper studies a VGLUT3 variant causing DFNA25 deafness, showing fused stereocilia bundles and elongated synaptic ribbons in a mouse model.