MicrobiologybioRxivPreprint
Mycobacteriophage D29-Derived LysB Enhances Anti-Tubercular Therapy in Experimental Pulmonary Tuberculosis
Sunil Kumar Raman, Rahul Sharma, Rutuja Gangakhedkar…·Amit Kumar Singh
This study shows that intranasal administration of D29 LysB enhances the effectiveness of standard antitubercular therapy in murine and guinea pig models of tuberculosis by reducing bacterial load and improving tissue pathology.