Plant BiologyNature CommunicationsPeer-reviewed
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Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
Samuel Edward Hakim, Nancy Choudhary, Karan Malhotra…·Jakob Franke
Comparing nine Solanaceae genomes reveals a conserved withanolide gene cluster; three of its P450s, expressed in yeast and N. benthamiana, oxidise 24-methyldesmosterol toward the withanoside V aglycone.
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