Frédérique Braun

The paper identifies new Rae1 cleavage sites and shows that ribosome stalling and collisions trigger mRNA decay in Bacillus subtilis, with sequence context influencing cleavage efficiency.

This study identifies a new Rae1 target, fliY mRNA, and shows Rae1 cleavage occurs upstream of stalled ribosomes, not in the A-site, revealing a novel mechanism for mRNA cleavage.

The paper identifies unconventional mRNA processing and degradation pathways for the polycistronic yrzI mRNA in B. subtilis, involving translation-dependent cleavage and 3'-exoribonuclease action.

The paper identifies endonucleolytic cleavage sites in Bacillus subtilis using transcriptome-wide mapping and deep mutational scanning, revealing distinct sequence determinants for different endoribonucleases.