Author

Lun Xu

Shanghai Medical College of Fudan UniversityORCID 0000-0001-5873-6924Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1

Frequent Co-Authors

Jérôme GolebiowskiiD· 2 shared Jody PacaloniD· 2 shared Xiaojing CongiD· 2 shared Yiqun YuiD· 2 shared Christine BelloiriD· 1 shared Claire A. de MarchiD· 1 shared Hiroaki MatsunamiiD· 1 shared Jérémie TopiniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Jérôme GolebiowskiORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Biological ChemistryPeer-reviewedAug 1, 2022

Extracellular loop 2 of G protein-coupled olfactory receptors is critical for odorant recognition

Yiqun Yu, Zhenjie Ma, Jody Pacalon…·Xiaojing Cong

This study shows that ECL2 in GPCRs is crucial for odorant recognition and promiscuity, enabling virtual screening of ligands with high success.

28 citations

statistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJan 6, 2020

Functions of olfactory receptors are decoded from their sequence

Xiaojing Cong, Wenwen Ren, Jody Pacalon…·Jérôme Golebiowski

The paper uses machine learning to predict olfactory receptor-odorant pairs and basal activity from sequence data, identifying key residues that determine selectivity and activity.

5 citations

protein sequencemachine learning (classical)

𝕏 PostBluesky